Northwestern University Comprehensive Transplant Center
Northwestern University Comprehensive Transplant Center: One of the major research initiatives of the Comprehensive Transplant Center (CTC) at Northwestern Feinberg School of Medicine, led by Dr. Michael Abecassis, the founding director of the CTC, is the Northwestern University Collaborative in Transplant Related Immunology and Biomedical Engineering (NUCTRIBE)
Dr. Abecassis recently recruited Dr. Jason Wertheim into NUCTRIBE to develop and direct a program focused on advancing the state of art in organ regeneration and tissue engineered solutions to solve the organ shortage that currently limits wider application of transplants as life-saving procedures.
In collaboration with Northwestern University’s Institute for BioNanotechnology in Medicine (IBNAM), the CTC is pursuing tissue engineered approaches to rehabilitating extracellular matrices derived from cross-species organs reconstituting these biologic scaffolds with human-derived cells, in addition to the more traditional models in tissue engineering that involve growing cells on synthetic polymer scaffolds to recreate the organ or tissue of interest. The CTC is particularly interested in using BioNanotechnology through a targeted approach to manipulate cell homing, differentiation, and proliferation, modifying both biologic and synthetic scaffolds in order to eventually regenerate failing organs as well as creating new ones .