SynGenSys Limited
SynGenSys builds synthetic promoter systems for exceptional control of gene expression, yield, tissue targeting, host cell compatibility and promoter size. We drive unmatched efficiency in biopharmaceutical manufacturing and faster, better outcomes for cell and gene therapy developers.
Description
Syngensys provides both off the shelf and bespoke development of advanced gene expression systems for biopharmaceutical manufacturing and gene and cell therapy applications.
Our biomanufacturing portfolio contains a library of ready-to-use gene promoters designed for use with CHO based biopharmaceutical manufacturing systems to enhance yields, improve stability, reduce cost and provide faster turn-around, even with difficult to express proteins.
Our cell and gene therapy portfolio contains promoter sets designed for applications targeting Liver, Muscle and NK tissues, designed to meet the size requirements of AAV delivery vectors and engineered to provide expression strength, durability and specificity tuned to therapeutic requirements.
Our bespoke promoter design and validation service uses our unique computational transcription analysis toolset to map the transcriptional landscape of target tissues, followed with proprietary design tools and deep expertise to identify critical factors of gene regulation required to support therapeutic or manufacturing outcomes. We design synthetic promoters, engineered for safety, efficacy and stability to meet the specific requirements of each customer requirement.
