2018 Annual Report - Europe


This quarterly data report details industry-specific statistics compiled from hundreds of cell therapy, gene therapy, tissue engineering, and other regenerative medicine therapeutic developers worldwide, including total financings, partnerships and other deals, clinical trial information, key clinical data events, and ARM’s current strategic priorities.


This quarterly data report details industry-specific statistics compiled from hundreds of cell therapy, gene therapy, tissue engineering, and other regenerative medicine therapeutic developers worldwide, including total financings, partnerships and other deals, clinical trial information, key clinical data events, and ARM’s current strategic priorities.

European Sector Landscape

241+

Regenerative Medicine / Advanced Therapies
Companies based in Europe/Israel

United Kingdom55Switzerland16Sweeden11Spain13Slovenia1Portugal3Poland1Norway3The Netherlands14Lithuania1Italy8Israel24Ireland6Greece1Germany27France29Finland3Denmark2Czech Republic3Belgium13Austria7

Total 2018 European/Israeli Financings

Total
Global Financing

$2.2 Billion
Approximately €1.9 Billion

 40%

Increase from 2017

Gene & Gene-modified
Cell Therapy

$1.9 Billion
Approximately €1.7 Billion

 117%

Increase from 2017

Cell
Therapy

$884.7 Million
Approximately €885 Million

 2%

Decrease from 2017

Tissue
Engineering

$73.3 Million
Approximately €64 Million

 41%

Decrease from 2017

216

Clinical Trials
Sponsored by a European or Israeli
developer as of EOY 2018

Clinical Trial by Technology Type

Clinical Trials by Phase

19.4%64.4%16.2%030405060708090100110120130140Phase 1Phase 2Phase 3
Gene Therapy
17.9%64.2%17.9%01520253035404550556065Phase 1Phase 2Phase 3
Cell Therapy
9.4%69.8%20.8%0510152025303540Phase 1Phase 2Phase 3
Gene-Modified
Cell Therapy
32.8%58.6%8.6%05101520253035Phase 1Phase 2Phase 3
Tissue Engineering
10.0%70.0%20.0%01234567Phase 1Phase 2Phase 3

Clinical Trials by Indication: EOY 2018

Oncology
103
Hematology
18
Cardiovascular
17
Ophthalmology
16
Endocrine Metabolic & Genetic Disorders
12
Musculoskeletal
11
Immunology & Inflammation
10
Dermatology
9
Central Nervous System
6
Infectious Disease
5
Gastroenterology
3
Genitourinary Disorders
3
Respiratory
1
Lymphatic Diseases
1
Surgery
1